Why must NSAIDs be used cautiously in senior dogs?

• A. They can cause no side effects in any dog
• B. They are approved for long-term use in all senior dogs
• C. They can affect kidneys, liver, and stomach; require veterinary supervision and appropriate dosing
• D. They can be given safely without veterinary consultation if the dog seems comfortable

Answer: (C)

NSAIDs must be used cautiously in senior dogs because they can affect the kidneys, liver, and stomach, and they require veterinary supervision and appropriate dosing. These drugs reduce inflammation by blocking enzymes that also help protect the stomach lining and support kidney blood flow and liver metabolism. In older dogs, organ function may already be diminished or compromised by chronic disease, dehydration, or other medications, so NSAIDs can more easily cause stomach ulcers or irritation, kidney injury, or liver strain. That’s why a veterinarian typically checks baseline kidney and liver function, considers the dog’s overall health and other drugs, and tailors the dose and duration. Ongoing monitoring is important to catch any signs of trouble early. Look for vomiting, loss of appetite, dark stools, thirst or urination changes, lethargy, or abdominal discomfort, and contact the vet if they appear. While NSAIDs can be helpful, they are not universally safe for all senior dogs and must be used with professional guidance.